Title : [Effect of rapamycin on high glucose-induced autophagy impairment, oxidative stress and premature senescence in rat mesangial cells in vitro].

Pub. Date : 2012 Apr

PMID : 22543123






1 Functional Relationships(s)
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1 RESULTS: Compared with those of normal cell culture, the cells exposed to high glucose for 72 h and 10 days showed down-regulated LC3 expression, up-regulated p62/SQSTM1 expression, elevated MDA and protein carbonyl levels, and increased SAHF formation and percentage of SA-beta-gal-positive cells. Glucose KH RNA binding domain containing, signal transduction associated 1 Rattus norvegicus