Title : Oligomerization of ZFYVE27 (Protrudin) is necessary to promote neurite extension.

Pub. Date : 2011

PMID : 22216323






4 Functional Relationships(s)
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1 To decipher the oligomeric nature of ZFYVE27, we performed sucrose gradient centrifugation and showed that ZFYVE27 oligomerizes into dimer/tetramer forms. Sucrose zinc finger FYVE-type containing 27 Homo sapiens
2 To decipher the oligomeric nature of ZFYVE27, we performed sucrose gradient centrifugation and showed that ZFYVE27 oligomerizes into dimer/tetramer forms. Sucrose zinc finger FYVE-type containing 27 Homo sapiens
3 Sub-cellular fractionation and Triton X-114 membrane phase separation analysis indicated that ZFYVE27 is a peripheral membrane protein. Nonidet P-40 zinc finger FYVE-type containing 27 Homo sapiens
4 Furthermore, ZFYVE27 also binds to phosphatidylinositol 3-phosphate lipid moiety. phosphatidylinositol 3-phosphate lipid zinc finger FYVE-type containing 27 Homo sapiens