Title : Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation.

Pub. Date : 1990 Nov 1

PMID : 2215607






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 BACKGROUND AND METHODS: The plasma cholesteryl-ester transfer protein (CETP) catalyzes the transfer of cholesteryl esters from high-density lipoprotein (HDL) to other lipoproteins. Cholesterol Esters cholesteryl ester transfer protein Homo sapiens
2 BACKGROUND AND METHODS: The plasma cholesteryl-ester transfer protein (CETP) catalyzes the transfer of cholesteryl esters from high-density lipoprotein (HDL) to other lipoproteins. Cholesterol Esters cholesteryl ester transfer protein Homo sapiens
3 Family members homozygous for CETP deficiency (n = 10) had moderate hypercholesterolemia (mean total cholesterol level [+/- SD], 7.01 +/- 0.83 mmol per liter), markedly increased levels of HDL cholesterol (4.24 +/- 1.01 mmol per liter) and apolipoprotein A-I, and decreased levels of low-density lipoprotein cholesterol (1.99 +/- 0.80 mmol per liter) and apolipoprotein B. Cholesterol cholesteryl ester transfer protein Homo sapiens
4 Family members homozygous for CETP deficiency (n = 10) had moderate hypercholesterolemia (mean total cholesterol level [+/- SD], 7.01 +/- 0.83 mmol per liter), markedly increased levels of HDL cholesterol (4.24 +/- 1.01 mmol per liter) and apolipoprotein A-I, and decreased levels of low-density lipoprotein cholesterol (1.99 +/- 0.80 mmol per liter) and apolipoprotein B. Cholesterol cholesteryl ester transfer protein Homo sapiens
5 CETP deficiency was not found in six unrelated subjects with elevated HDL cholesterol levels who were from different parts of the United States. Cholesterol cholesteryl ester transfer protein Homo sapiens