Title : Resistance emergence mechanism and mechanism of resistance suppression by tobramycin for cefepime for Pseudomonas aeruginosa.

Pub. Date : 2012 Jan

PMID : 22005996






2 Functional Relationships(s)
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1 Cefepime is a cephalosporin whose 3" side chain provides some stability against AmpC beta-lactamases. Cefepime beta-lactamase Pseudomonas aeruginosa PAO1
2 We examined the activity of cefepime against P. aeruginosa wild-type strain PAO1 and its isogenic AmpC stably derepressed mutant in our hollow-fiber infection model. Cefepime beta-lactamase Pseudomonas aeruginosa PAO1