Title : Down-regulation of FUT3 and FUT5 by shRNA alters Lewis antigens expression and reduces the adhesion capacities of gastric cancer cells.

Pub. Date : 2011 Dec

PMID : 21978830






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Fucosyltransferases are enzymes that add fucose to precursor glycan structures: FUT3 and FUT5 catalyze the addition of fucose to the alpha1-3,4 position and are detected in epithelial cells. Fucose fucosyltransferase 5 Homo sapiens
2 Fucosyltransferases are enzymes that add fucose to precursor glycan structures: FUT3 and FUT5 catalyze the addition of fucose to the alpha1-3,4 position and are detected in epithelial cells. Polysaccharides fucosyltransferase 5 Homo sapiens
3 Fucosyltransferases are enzymes that add fucose to precursor glycan structures: FUT3 and FUT5 catalyze the addition of fucose to the alpha1-3,4 position and are detected in epithelial cells. Fucose fucosyltransferase 5 Homo sapiens
4 The adhesion to endothelial cells trough the binding to E-selectin, and the binding to hyaluronic acid were reduced in the shFUT3, shFUT5 and shFUT3/FUT5, whereas the levels of CD44, analyzed by western blot, did not change. Hyaluronic Acid fucosyltransferase 5 Homo sapiens