Title : MiR-129-5p is required for histone deacetylase inhibitor-induced cell death in thyroid cancer cells.

Pub. Date : 2011 Dec

PMID : 21946411






3 Functional Relationships(s)
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1 Two HDACi, trichostatin A and vorinostat, induced miR-129-5p overexpression, histone acetylation and cell death in BCPAP, TPC-1, 8505C, and CAL62 cell lines and in primary cultures of papillary thyroid cancer (PTC) cells. trichostatin A microRNA 1295a Homo sapiens
2 Two HDACi, trichostatin A and vorinostat, induced miR-129-5p overexpression, histone acetylation and cell death in BCPAP, TPC-1, 8505C, and CAL62 cell lines and in primary cultures of papillary thyroid cancer (PTC) cells. Vorinostat microRNA 1295a Homo sapiens
3 Moreover, miR-129-5p accentuated the anti-proliferative effects of other cancer drugs such as etoposide or human alpha-lactalbumin made lethal for tumor cells (HAMLET). Etoposide microRNA 1295a Homo sapiens