Title : FABP7 expression in normal and stab-injured brain cortex and its role in astrocyte proliferation.

Pub. Date : 2011 Nov

PMID : 21938553






3 Functional Relationships(s)
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1 Brain-type fatty acid-binding protein (FABP7) is abundantly expressed in neural stem cells and astrocytes of developing brain, suggesting its role in differentiation and/or proliferation of glial cells through regulation of lipid metabolism and/or signaling. Fatty Acids fatty acid binding protein 7, brain Mus musculus
2 Primary cultured astrocytes from FABP7-KO mice also showed a significant decrease in proliferation and omega-3 fatty acid incorporation compared with wild-type astrocytes. Fatty Acids, Omega-3 fatty acid binding protein 7, brain Mus musculus
3 Overall, these data suggest that FABP7 is involved in the proliferation of astrocytes by controlling cellular fatty acid homeostasis. Fatty Acids fatty acid binding protein 7, brain Mus musculus