Title : Investigation of the binding of roxatidine acetate hydrochloride with cyclomaltoheptaose (β-cyclodextrin) using IR and NMR spectroscopy.

Pub. Date : 2011 Sep 27

PMID : 21816394






4 Functional Relationships(s)
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1 NMR chemical shift changes of the cyclomaltoheptaose (beta-cyclodextrin, beta-CD) cavity protons as well as roxatidine acetate hydrochloride aromatic ring protons revealed the formation of a RAH-beta-CD inclusion complex. betadex RAB34, member RAS oncogene family Homo sapiens
2 NMR chemical shift changes of the cyclomaltoheptaose (beta-cyclodextrin, beta-CD) cavity protons as well as roxatidine acetate hydrochloride aromatic ring protons revealed the formation of a RAH-beta-CD inclusion complex. betadex RAB34, member RAS oncogene family Homo sapiens
3 NMR chemical shift changes of the cyclomaltoheptaose (beta-cyclodextrin, beta-CD) cavity protons as well as roxatidine acetate hydrochloride aromatic ring protons revealed the formation of a RAH-beta-CD inclusion complex. roxatidine acetate RAB34, member RAS oncogene family Homo sapiens
4 The NOESY spectrum confirmed the selective penetration of the aromatic ring of RAH into the beta-CD cavity in comparison to that of the piperidine ring. betadex RAB34, member RAS oncogene family Homo sapiens