Title : Knockdown of ornithine decarboxylase antizyme 1 causes loss of uptake regulation leading to increased N1, N11-bis(ethyl)norspermine (BENSpm) accumulation and toxicity in NCI H157 lung cancer cells.

Pub. Date : 2012 Feb

PMID : 21814790






2 Functional Relationships(s)
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Protein Name
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1 Knockdown of ornithine decarboxylase antizyme 1 causes loss of uptake regulation leading to increased N1, N11-bis(ethyl)norspermine (BENSpm) accumulation and toxicity in NCI H157 lung cancer cells. N(1),N(11)-diethylnorspermine ornithine decarboxylase antizyme 1 Homo sapiens
2 Antizyme 1 knockdown clones accumulated greater amounts of the polyamine analogue N (1),N (11)-bis(ethyl)norspermine (BENSpm) and were more sensitive to analogue treatment. N(1),N(11)-diethylnorspermine ornithine decarboxylase antizyme 1 Homo sapiens