Title : Construction of an Escherichia coli strain which excretes abnormally large amounts of adenosine 3',5'-cyclic monophosphate.

Pub. Date : 1978 Nov

PMID : 217515






4 Functional Relationships(s)
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1 It has previously been shown that an Escherichia coli CRP- strain 5333 accumulates abnormally large amounts of adenosine 3",5"-cyclic monophosphate (cAMP). Cyclic AMP catabolite gene activator protein Escherichia coli
2 It has previously been shown that an Escherichia coli CRP- strain 5333 accumulates abnormally large amounts of adenosine 3",5"-cyclic monophosphate (cAMP). Cyclic AMP catabolite gene activator protein Escherichia coli
3 Using P1 transduction, the CRP- character was transferred to E. coli Crookes strain which is deficient for cAMP phophodiesterase (CPD-). Cyclic AMP catabolite gene activator protein Escherichia coli
4 The resulting strain HY22 (CRP-, CPD-) accumulates greater amounts of cAMP both intracellularly and extracellularly than does 5333. Cyclic AMP catabolite gene activator protein Escherichia coli