Title : The mechanism of enzymatic and non-enzymatic N-oxide reductive metabolism of cyadox in pig liver.

Pub. Date : 2011 Nov

PMID : 21745143






3 Functional Relationships(s)
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1 It is found that cyadox can be enzymatically reduced to 4-cyadox monoxide and 1-cyadox monoxide; this process is catalyzed by aldehyde oxidase and xanthine oxidase in the cytosol and by cytochrome b5 reductase in the microsomes. cyadox aldehyde oxidase 1 Sus scrofa
2 It is found that cyadox can be enzymatically reduced to 4-cyadox monoxide and 1-cyadox monoxide; this process is catalyzed by aldehyde oxidase and xanthine oxidase in the cytosol and by cytochrome b5 reductase in the microsomes. cyadox xanthine dehydrogenase Sus scrofa
3 On the other hand, cyadox is only reduced to 4-cyadox monoxide in the non-enzymatic reduction mediated by heme groups of catalase and cytochrome P450s. cyadox catalase Sus scrofa