Pub. Date : 2012 Jan-Feb
PMID : 21733940
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Anti-beta(2)GP1 antibodies significantly reduced platelet aggregation (percentage area under the curve; %AUC) in a concentration-dependent manner using both 5 mumol/L (P < .001) and 2.5 mumol/L (P = .038) ADP but did not significantly affect the rate of aggregation. | Adenosine Diphosphate | GTP binding protein 1 | Homo sapiens |
| 2 | These results suggest (1) interactions and effects of antiphospholipid antibodies on platelets are agonist and concentration dependent and (2) anti-beta(2)GP1 antibodies may inhibit dense granule release and/or inhibition of the arachidonic acid pathway. | Arachidonic Acid | GTP binding protein 1 | Homo sapiens |