Pub. Date : 2011 May 20
PMID : 21454566
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Second, MGL degrades 2-arachidonoyl glycerol (2-AG), the most abundant endogenous ligand of cannabinoid receptors (CBR). | glyceryl 2-arachidonate | monoglyceride lipase | Mus musculus |
| 2 | Second, MGL degrades 2-arachidonoyl glycerol (2-AG), the most abundant endogenous ligand of cannabinoid receptors (CBR). | glyceryl 2-arachidonate | monoglyceride lipase | Mus musculus |
| 3 | Nonetheless, fasted MGL-ko mice exhibit reduced plasma glycerol and triacylglycerol, as well as liver triacylglycerol levels indicative for impaired lipolysis. | Glycerol | monoglyceride lipase | Mus musculus |
| 4 | Nonetheless, fasted MGL-ko mice exhibit reduced plasma glycerol and triacylglycerol, as well as liver triacylglycerol levels indicative for impaired lipolysis. | Triglycerides | monoglyceride lipase | Mus musculus |
| 5 | Nonetheless, fasted MGL-ko mice exhibit reduced plasma glycerol and triacylglycerol, as well as liver triacylglycerol levels indicative for impaired lipolysis. | Triglycerides | monoglyceride lipase | Mus musculus |
| 6 | Yet mice lacking MGL show a pharmacological tolerance to the CBR agonist CP 55,940 suggesting that the elevated 2-AG levels are functionally antagonized by desensitization of CBR. | cp 55 | monoglyceride lipase | Mus musculus |
| 7 | Yet mice lacking MGL show a pharmacological tolerance to the CBR agonist CP 55,940 suggesting that the elevated 2-AG levels are functionally antagonized by desensitization of CBR. | glyceryl 2-arachidonate | monoglyceride lipase | Mus musculus |
| 8 | Interestingly, however, MGL-ko mice receiving a high fat diet exhibit significantly improved glucose tolerance and insulin sensitivity in comparison with wild-type controls despite equal weight gain. | Glucose | monoglyceride lipase | Mus musculus |