Title : Melatonin agonists in primary insomnia and depression-associated insomnia: are they superior to sedative-hypnotics?

Pub. Date : 2011 Jun 1

PMID : 21453740






4 Functional Relationships(s)
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1 The novel antidepressant agomelatine, a dual action agent with affinity for melatonin MT1 and MT2 receptors and 5-HT2c antagonistic properties, constitutes a new approach to the treatment of major depressive disorders. agomelatine metallothionein 1I, pseudogene Homo sapiens
2 The novel antidepressant agomelatine, a dual action agent with affinity for melatonin MT1 and MT2 receptors and 5-HT2c antagonistic properties, constitutes a new approach to the treatment of major depressive disorders. agomelatine metallothionein 2A Homo sapiens
3 Taken together, the evidence indicates that MT1/MT2 receptor agonists like ramelteon or agomelatine may be valuable pharmacological tools for insomnia and for depression-associated insomnia. agomelatine metallothionein 1I, pseudogene Homo sapiens
4 Taken together, the evidence indicates that MT1/MT2 receptor agonists like ramelteon or agomelatine may be valuable pharmacological tools for insomnia and for depression-associated insomnia. agomelatine metallothionein 2A Homo sapiens