Title : Regulation of glycosyltransferases and Lewis antigens expression by IL-1β and IL-6 in human gastric cancer cells.

Pub. Date : 2011 Feb

PMID : 21365246






2 Functional Relationships(s)
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1 The activation of FUT1, FUT2 and FUT4 by IL-1beta is through the NF-kappaB pathway and the down-regulation of FUT3 and FUT5 by IL-6 is through the gp130/STAT-3 pathway, since they are inhibited specifically by panepoxydone and AG490, respectively. panepoxydone fucosyltransferase 5 Homo sapiens
2 The activation of FUT1, FUT2 and FUT4 by IL-1beta is through the NF-kappaB pathway and the down-regulation of FUT3 and FUT5 by IL-6 is through the gp130/STAT-3 pathway, since they are inhibited specifically by panepoxydone and AG490, respectively. alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide fucosyltransferase 5 Homo sapiens