Title : FPTB, a novel CA-4 derivative, induces cell apoptosis of human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress pathways.

Pub. Date : 2011 Feb

PMID : 21268067






1 Functional Relationships(s)
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1 FPTB also induced cell death mediated by increasing ER stress, GPR78 activation, and Ca(2+) release, which subsequently triggers calpain, caspase-12 and caspase-3 activity, resulting in apoptosis. FPTB G protein-coupled receptor 78 Homo sapiens