Title : A novel single-chain-Fv antibody against connective tissue growth factor attenuates bleomycin-induced pulmonary fibrosis in mice.

Pub. Date : 2011 Apr

PMID : 21265950






4 Functional Relationships(s)
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1 A novel single-chain-Fv antibody against connective tissue growth factor attenuates bleomycin-induced pulmonary fibrosis in mice. Bleomycin cellular communication network factor 2 Mus musculus
2 In the present study, the protective effect of anti-CTGF scFv against bleomycin (BL)-induced pulmonary fibrosis was investigated in mice. Bleomycin cellular communication network factor 2 Mus musculus
3 In the present study, the protective effect of anti-CTGF scFv against bleomycin (BL)-induced pulmonary fibrosis was investigated in mice. Bleomycin cellular communication network factor 2 Mus musculus
4 Anti-CTGF scFv significantly reduced the numbers of inflammatory leukocytes (total and differential count) in BAL fluid, as well as the hydroxyproline content of lung tissue. Hydroxyproline cellular communication network factor 2 Mus musculus