Pub. Date : 2011 Aug 1
PMID : 21186792
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Small interfering RNA knocks down the molecular target of alendronate, farnesyl pyrophosphate synthase, in osteoclast and osteoblast cultures. | Alendronate | farnesyl diphosphate synthetase | Mus musculus |
| 2 | Farnesyl pyrophosphate synthase (FPPS), an enzyme in the mevalonate pathway, is the inhibition target of alendronate, a potent FDA-approved nitrogen-containing bisphosphonate (N-BP) drug, at the molecular level. | Mevalonic Acid | farnesyl diphosphate synthetase | Mus musculus |
| 3 | Farnesyl pyrophosphate synthase (FPPS), an enzyme in the mevalonate pathway, is the inhibition target of alendronate, a potent FDA-approved nitrogen-containing bisphosphonate (N-BP) drug, at the molecular level. | Mevalonic Acid | farnesyl diphosphate synthetase | Mus musculus |
| 4 | Farnesyl pyrophosphate synthase (FPPS), an enzyme in the mevalonate pathway, is the inhibition target of alendronate, a potent FDA-approved nitrogen-containing bisphosphonate (N-BP) drug, at the molecular level. | Alendronate | farnesyl diphosphate synthetase | Mus musculus |
| 5 | Farnesyl pyrophosphate synthase (FPPS), an enzyme in the mevalonate pathway, is the inhibition target of alendronate, a potent FDA-approved nitrogen-containing bisphosphonate (N-BP) drug, at the molecular level. | Alendronate | farnesyl diphosphate synthetase | Mus musculus |
| 6 | Farnesyl pyrophosphate synthase (FPPS), an enzyme in the mevalonate pathway, is the inhibition target of alendronate, a potent FDA-approved nitrogen-containing bisphosphonate (N-BP) drug, at the molecular level. | nitrogen-containing bisphosphonate | farnesyl diphosphate synthetase | Mus musculus |
| 7 | Farnesyl pyrophosphate synthase (FPPS), an enzyme in the mevalonate pathway, is the inhibition target of alendronate, a potent FDA-approved nitrogen-containing bisphosphonate (N-BP) drug, at the molecular level. | nitrogen-containing bisphosphonate | farnesyl diphosphate synthetase | Mus musculus |
| 8 | Farnesyl pyrophosphate synthase (FPPS), an enzyme in the mevalonate pathway, is the inhibition target of alendronate, a potent FDA-approved nitrogen-containing bisphosphonate (N-BP) drug, at the molecular level. | n-bp | farnesyl diphosphate synthetase | Mus musculus |
| 9 | Farnesyl pyrophosphate synthase (FPPS), an enzyme in the mevalonate pathway, is the inhibition target of alendronate, a potent FDA-approved nitrogen-containing bisphosphonate (N-BP) drug, at the molecular level. | n-bp | farnesyl diphosphate synthetase | Mus musculus |