Title : Retinoic acid receptor-mediated signaling protects cardiomyocytes from hyperglycemia induced apoptosis: role of the renin-angiotensin system.

Pub. Date : 2011 May

PMID : 20945395






1 Functional Relationships(s)
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1 Decreased nuclear expression of RARalpha and RXRalpha, activation of apoptotic signaling and cell apoptosis was observed in high glucose (HG) treated neonatal and adult cardiomyocytes and diabetic hearts in Zucker diabetic fatty (ZDF) rats. Glucose retinoid X receptor alpha Rattus norvegicus