Pub. Date : 2011 Jun
PMID : 20846698
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Regulation of synthesis and oxidation of fatty acids by adiponectin receptors (AdipoR1/R2) and insulin receptor substrate isoforms (IRS-1/-2) of the liver in a nonalcoholic steatohepatitis animal model. | Fatty Acids | adiponectin receptor 1 | Rattus norvegicus |
| 2 | Adiponectin receptors (AdipoR1/R2) and insulin receptor substrates (IRS-1/-2) are known as modulators of these fatty acid metabolisms in the liver; however, the regulatory roles of these receptors in the synthesis and oxidation of fatty acids are unclear in the liver of NASH. | Fatty Acids | adiponectin receptor 1 | Rattus norvegicus |
| 3 | Adiponectin receptors (AdipoR1/R2) and insulin receptor substrates (IRS-1/-2) are known as modulators of these fatty acid metabolisms in the liver; however, the regulatory roles of these receptors in the synthesis and oxidation of fatty acids are unclear in the liver of NASH. | Fatty Acids | adiponectin receptor 1 | Rattus norvegicus |
| 4 | As a result of the decrease of AdipoR1/R2 expression, the messenger RNA expression levels of genes located downstream of AdipoR1/R2, adenosine monophosphate-activated protein kinase alpha1/alpha2, which inhibits fatty acid synthesis, and peroxisome proliferator-activated receptor alpha, which activates fatty acid oxidation, also decreased. | Fatty Acids | adiponectin receptor 1 | Rattus norvegicus |
| 5 | As a result of the decrease of AdipoR1/R2 expression, the messenger RNA expression levels of genes located downstream of AdipoR1/R2, adenosine monophosphate-activated protein kinase alpha1/alpha2, which inhibits fatty acid synthesis, and peroxisome proliferator-activated receptor alpha, which activates fatty acid oxidation, also decreased. | Fatty Acids | adiponectin receptor 1 | Rattus norvegicus |
| 6 | As a result of the decrease of AdipoR1/R2 expression, the messenger RNA expression levels of genes located downstream of AdipoR1/R2, adenosine monophosphate-activated protein kinase alpha1/alpha2, which inhibits fatty acid synthesis, and peroxisome proliferator-activated receptor alpha, which activates fatty acid oxidation, also decreased. | Fatty Acids | adiponectin receptor 1 | Rattus norvegicus |
| 7 | As a result of the decrease of AdipoR1/R2 expression, the messenger RNA expression levels of genes located downstream of AdipoR1/R2, adenosine monophosphate-activated protein kinase alpha1/alpha2, which inhibits fatty acid synthesis, and peroxisome proliferator-activated receptor alpha, which activates fatty acid oxidation, also decreased. | Fatty Acids | adiponectin receptor 1 | Rattus norvegicus |