Pub. Date : 2011 Feb
PMID : 20724079
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Interleukin-15 affects serotonin system and exerts antidepressive effects through IL15Ralpha receptor. | Serotonin | interleukin 15 receptor, alpha chain | Mus musculus |
| 2 | Fluoxetine (the classic antidepressant Prozac, which inhibits 5-HT(2C) and SERT) reduced the immobility of the IL15Ralpha knockout mice in comparison with their pretreatment baseline. | Fluoxetine | interleukin 15 receptor, alpha chain | Mus musculus |
| 3 | Fluoxetine (the classic antidepressant Prozac, which inhibits 5-HT(2C) and SERT) reduced the immobility of the IL15Ralpha knockout mice in comparison with their pretreatment baseline. | Fluoxetine | interleukin 15 receptor, alpha chain | Mus musculus |
| 4 | Together with the unchanged performance of the IL15Ralpha knockout mice on the rotarod, this response to fluoxetine indicates that the immobility reflects depression. | Fluoxetine | interleukin 15 receptor, alpha chain | Mus musculus |
| 5 | Thus, the effect of IL15 on serotonin transmission may underlie the depressive-like behavior of IL15Ralpha knockout mice. | Serotonin | interleukin 15 receptor, alpha chain | Mus musculus |