Pub. Date : 2010 Sep
PMID : 20693878
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | METHODS: We used the whole cell, patch clamp technique to test whether duloxetine interacts with the neuronal Nav1.7 Na+ channel as a potential target. | Duloxetine Hydrochloride | sodium voltage-gated channel alpha subunit 9 | Homo sapiens |
| 2 | Resting and inactivated Nav1.7 Na+ channel block by duloxetine were measured by conventional pulse protocols in transfected human embryonic kidney cells. | Duloxetine Hydrochloride | sodium voltage-gated channel alpha subunit 9 | Homo sapiens |
| 3 | Finally, duloxetine elicited strong use-dependent block of neuronal transient Nav1.7 Na+ currents during repetitive stimulations. | Duloxetine Hydrochloride | sodium voltage-gated channel alpha subunit 9 | Homo sapiens |