Title : Aspirin and alterations in DNA repair proteins in the SW480 colorectal cancer cell line.

Pub. Date : 2010 Jul

PMID : 20514442






2 Functional Relationships(s)
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1 Although a correlation was not seen between transcript and protein levels of ATR, BRCA1 and GADD45alpha, an increase in XRCC3 encoded protein expression upon aspirin treatment in SW480 cells was observed by immunoblotting, immunofluorescence and immunohistochemical analysis. Aspirin X-ray repair cross complementing 3 Homo sapiens
2 This is the first report of XRCC3 gene transcription and encoded protein expression being susceptible to exposure to the non-steroidal anti-inflammatory drug, aspirin. Aspirin X-ray repair cross complementing 3 Homo sapiens