Title : Effects of thyrotropin and thyrotropin-receptor-stimulating Graves' disease immunoglobulin G on cyclic adenosine monophosphate and hyaluronan production in nondifferentiated orbital fibroblasts of Graves' ophthalmopathy patients.

Pub. Date : 2010 May

PMID : 20384487






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 BACKGROUND: Orbital fibroblasts are involved in the pathogenesis of Graves" ophthalmopathy (GO) by producing hyaluronan (HA), synthesized by three types of hyaluronan synthases (HAS1, HAS2, and HAS3). Hyaluronic Acid hyaluronan synthase 3 Homo sapiens
2 BACKGROUND: Orbital fibroblasts are involved in the pathogenesis of Graves" ophthalmopathy (GO) by producing hyaluronan (HA), synthesized by three types of hyaluronan synthases (HAS1, HAS2, and HAS3). Hyaluronic Acid hyaluronan synthase 3 Homo sapiens
3 RESULTS: FSK significantly stimulated cAMP production, HAS1 and HAS3 mRNA expression, and HA secretion in orbital fibroblasts. Colforsin hyaluronan synthase 3 Homo sapiens