Title : Macaque CYP2C76 encodes cytochrome P450 enzyme not orthologous to any human isozymes.

Pub. Date : 2010 Feb

PMID : 20359284






1 Functional Relationships(s)
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1 In cynomolgus monkey, we have identified cDNAs for 21 kinds of cytochromes P450 (CYPs), among which CYP2C76 does not correspond to any human CYP isozymes and is partly responsible for the difference in pitavastatin metabolism between cynomolgus monkey and human. pitavastatin cytochrome P450 family 2 subfamily C member 76 Macaca fascicularis