Title : 5-hydroxytryptamine-stimulated accumulation of 1,2-diacylglycerol in the rabbit basilar artery: a role for protein kinase C in smooth muscle contraction.

Pub. Date : 1991 Feb

PMID : 2015423






2 Functional Relationships(s)
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1 The 5-HT-induced accumulation of DG could be blocked with the putative phospholipase C inhibitor 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate (NCDC; 70 microM), but not with the protein kinase C inhibitor, 1-(5-isoquinolinesulphonyl)-2-methyl piperazine (H7; 50 microM). 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate LOC100009319 Oryctolagus cuniculus
2 The 5-HT-induced accumulation of DG could be blocked with the putative phospholipase C inhibitor 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate (NCDC; 70 microM), but not with the protein kinase C inhibitor, 1-(5-isoquinolinesulphonyl)-2-methyl piperazine (H7; 50 microM). 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate LOC100009319 Oryctolagus cuniculus