Title : Cloning and expression of the cDNA encoding human fumarylacetoacetate hydrolase, the enzyme deficient in hereditary tyrosinemia: assignment of the gene to chromosome 15.

Pub. Date : 1991 Mar

PMID : 1998338






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Transient expression of this FAH cDNA in transfected CV-1 mammalian cells resulted in the synthesis of an immunoreactive protein comigrating with purified human liver FAH on SDS-PAGE and having enzymatic activity as shown by the hydrolysis of the natural substrate fumarylacetoacetate. Sodium Dodecyl Sulfate fumarylacetoacetate hydrolase Homo sapiens
2 Transient expression of this FAH cDNA in transfected CV-1 mammalian cells resulted in the synthesis of an immunoreactive protein comigrating with purified human liver FAH on SDS-PAGE and having enzymatic activity as shown by the hydrolysis of the natural substrate fumarylacetoacetate. fumarylacetoacetate fumarylacetoacetate hydrolase Homo sapiens