Title : The role of calcium ions and calcium channel entry blockers in experimental ischemia-reperfusion-induced liver injury.

Pub. Date : 1991 Feb

PMID : 1992940






1 Functional Relationships(s)
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1 The possible activation of proteases converting the xanthine dehydrogenase to xanthine oxidase, the significant mitochondrial calcium loading during the ischemic period, and the potentiation of calcium and oxygen-derived free radicals to promote injury to mitochondria are mechanisms supported by this study, based on both histologic observations and on the pattern of enzyme leak after the acute ischemic event. Calcium xanthine dehydrogenase Rattus norvegicus