Title : Expression of prostate-specific membrane antigen (PSMA), increases cell folate uptake and proliferation and suggests a novel role for PSMA in the uptake of the non-polyglutamated folate, folic acid.

Pub. Date : 2010 Feb 15

PMID : 19830782






1 Functional Relationships(s)
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1 RESULTS: Proliferation of PC-3-PSMA cells grown in the presence of poly-gamma-glutamated folate, was significantly higher than that of PC-3-vector cells, an advantage which was attenuated by the addition of 2-PMPA. 2-(phosphonomethyl)pentanedioic acid folate hydrolase 1 Homo sapiens