Title : Lovastatin attenuates ionizing radiation-induced normal tissue damage in vivo.

Pub. Date : 2009 Sep

PMID : 19615773






1 Functional Relationships(s)
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1 RESULTS: Lovastatin attenuated IR-induced activation of NF-kappaB, mRNA expression of cell adhesion molecules and mRNA expression of pro-inflammatory and pro-fibrotic marker genes (i.e. TNFalpha, IL-6, TGFbeta, CTGF, and type I and type III collagen) in a tissue- and time-dependent manner. Lovastatin cellular communication network factor 2 Mus musculus