Pub. Date : 2009 May 13
PMID : 19415934
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | One of these genes, Afu4g14770, designated AfuOSC3, is clustered with genes of cytochrome P450 monooxygenases (P450s), a short-chain dehydrogenase/reductase (SDR), and acyltransferases, which presumably function in triterpene tailoring steps, suggesting that this gene cluster codes for helvolic acid biosynthesis. | Triterpenes | short-chain dehydrogenase/reductase | Saccharomyces cerevisiae S288C |
| 2 | One of these genes, Afu4g14770, designated AfuOSC3, is clustered with genes of cytochrome P450 monooxygenases (P450s), a short-chain dehydrogenase/reductase (SDR), and acyltransferases, which presumably function in triterpene tailoring steps, suggesting that this gene cluster codes for helvolic acid biosynthesis. | Triterpenes | short-chain dehydrogenase/reductase | Saccharomyces cerevisiae S288C |
| 3 | One of these genes, Afu4g14770, designated AfuOSC3, is clustered with genes of cytochrome P450 monooxygenases (P450s), a short-chain dehydrogenase/reductase (SDR), and acyltransferases, which presumably function in triterpene tailoring steps, suggesting that this gene cluster codes for helvolic acid biosynthesis. | helvolic acid | short-chain dehydrogenase/reductase | Saccharomyces cerevisiae S288C |
| 4 | One of these genes, Afu4g14770, designated AfuOSC3, is clustered with genes of cytochrome P450 monooxygenases (P450s), a short-chain dehydrogenase/reductase (SDR), and acyltransferases, which presumably function in triterpene tailoring steps, suggesting that this gene cluster codes for helvolic acid biosynthesis. | helvolic acid | short-chain dehydrogenase/reductase | Saccharomyces cerevisiae S288C |
| 5 | To further identify the function of triterpene tailoring enzymes, four P450 genes (CYP5081A1-D1) and a SDR gene (AfuSDR1) in the cluster were each coexpressed with AfuOSC3 in yeast. | Triterpenes | short-chain dehydrogenase/reductase | Saccharomyces cerevisiae S288C |