Title : Expression of multidrug resistance associated protein 5 (MRP5) on cornea and its role in drug efflux.

Pub. Date : 2009 Apr

PMID : 19323627






6 Functional Relationships(s)
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Protein Name
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1 Corneal efflux by MRP5 was studied with bis(POM)-PMEA and acyclovir using rabbit and human corneal epithelial cells along with MRP5 over expressing cells (MDCKII-MRP5). bis(pivaloyloxymethyl)-9-(2-phosphonylmethoxyethyl)adenine ATP binding cassette subfamily C member 5 Homo sapiens
2 Corneal efflux by MRP5 was studied with bis(POM)-PMEA and acyclovir using rabbit and human corneal epithelial cells along with MRP5 over expressing cells (MDCKII-MRP5). Acyclovir ATP binding cassette subfamily C member 5 Homo sapiens
3 MRP5 inhibitors also diminished PMEA and acyclovir efflux. adefovir ATP binding cassette subfamily C member 5 Homo sapiens
4 MRP5 inhibitors also diminished PMEA and acyclovir efflux. Acyclovir ATP binding cassette subfamily C member 5 Homo sapiens
5 Two well known antiglaucoma drugs, bimatoprost and latanoprost were rapidly effluxed by MRP5. Bimatoprost ATP binding cassette subfamily C member 5 Homo sapiens
6 Two well known antiglaucoma drugs, bimatoprost and latanoprost were rapidly effluxed by MRP5. Latanoprost ATP binding cassette subfamily C member 5 Homo sapiens