Pub. Date : 1991 Sep
PMID : 1923528
18 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To test this hypothesis, we used ras-transformed NIH3T3 cells that express an activated p21 containing valine (Val-12 p21) at position 12 instead of the normal glycine (Gly-12 p21) and a monoclonal antibody (mAb) designated DWP that is specific for the activated Val-12 ras proteins. | Valine | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 2 | To test this hypothesis, we used ras-transformed NIH3T3 cells that express an activated p21 containing valine (Val-12 p21) at position 12 instead of the normal glycine (Gly-12 p21) and a monoclonal antibody (mAb) designated DWP that is specific for the activated Val-12 ras proteins. | Valine | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 3 | To test this hypothesis, we used ras-transformed NIH3T3 cells that express an activated p21 containing valine (Val-12 p21) at position 12 instead of the normal glycine (Gly-12 p21) and a monoclonal antibody (mAb) designated DWP that is specific for the activated Val-12 ras proteins. | Valine | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 4 | To test this hypothesis, we used ras-transformed NIH3T3 cells that express an activated p21 containing valine (Val-12 p21) at position 12 instead of the normal glycine (Gly-12 p21) and a monoclonal antibody (mAb) designated DWP that is specific for the activated Val-12 ras proteins. | val-12 | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 5 | To test this hypothesis, we used ras-transformed NIH3T3 cells that express an activated p21 containing valine (Val-12 p21) at position 12 instead of the normal glycine (Gly-12 p21) and a monoclonal antibody (mAb) designated DWP that is specific for the activated Val-12 ras proteins. | Valine | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 6 | Culture fluids collected from NIH3T3 cells transformed by the activated Val-12 p21 were shown, using mAb DWP in a sandwich ELISA format, to contain the activated Val-12 p21. | val-12 | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 7 | Culture fluids collected from NIH3T3 cells transformed by the activated Val-12 p21 were shown, using mAb DWP in a sandwich ELISA format, to contain the activated Val-12 p21. | val-12 | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 8 | Culture fluids collected from NIH3T3 cells transformed by the activated Val-12 p21 were shown, using mAb DWP in a sandwich ELISA format, to contain the activated Val-12 p21. | (6aS,7S,9R,10aS)-7,10a-dimethyl-8-oxo-2-(phenylamino)-5,6,6a,7,8,9,10,10a-octahydrobenzo[h]quinazoline-9-carbonitrile | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 9 | Culture fluids collected from NIH3T3 cells transformed by the activated Val-12 p21 were shown, using mAb DWP in a sandwich ELISA format, to contain the activated Val-12 p21. | (6aS,7S,9R,10aS)-7,10a-dimethyl-8-oxo-2-(phenylamino)-5,6,6a,7,8,9,10,10a-octahydrobenzo[h]quinazoline-9-carbonitrile | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 10 | Culture fluids collected from NIH3T3 cells transformed by the activated Val-12 p21 were shown, using mAb DWP in a sandwich ELISA format, to contain the activated Val-12 p21. | val-12 | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 11 | Culture fluids collected from NIH3T3 cells transformed by the activated Val-12 p21 were shown, using mAb DWP in a sandwich ELISA format, to contain the activated Val-12 p21. | val-12 | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 12 | Employing mAb DWP as a detection reagent in the sandwich ELISA format, we were able to detect the Val-12 p21 in the plasma of the PSV-LM-EJ tumor-bearing mice. | (6aS,7S,9R,10aS)-7,10a-dimethyl-8-oxo-2-(phenylamino)-5,6,6a,7,8,9,10,10a-octahydrobenzo[h]quinazoline-9-carbonitrile | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 13 | Employing mAb DWP as a detection reagent in the sandwich ELISA format, we were able to detect the Val-12 p21 in the plasma of the PSV-LM-EJ tumor-bearing mice. | Valine | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 14 | Activated Val-12 p21 was not present in the plasma of non-tumor-bearing mice, or in the plasma of mice bearing SQ tumors composed of non-Val-12 p21 ras-transformed cells. | val-12 | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 15 | This report is the first description of an activated ras protein (Val-12 p21) in the plasma of tumor-bearing mice and demonstrates that the results of the Val-12 p21-specific ELISA could be validated with Western blot format. | Valine | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 16 | This report is the first description of an activated ras protein (Val-12 p21) in the plasma of tumor-bearing mice and demonstrates that the results of the Val-12 p21-specific ELISA could be validated with Western blot format. | Valine | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 17 | This report is the first description of an activated ras protein (Val-12 p21) in the plasma of tumor-bearing mice and demonstrates that the results of the Val-12 p21-specific ELISA could be validated with Western blot format. | val-12 | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 18 | This report is the first description of an activated ras protein (Val-12 p21) in the plasma of tumor-bearing mice and demonstrates that the results of the Val-12 p21-specific ELISA could be validated with Western blot format. | val-12 | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |