Pub. Date : 2009 Feb 26
PMID : 19137010
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have previously shown that the death receptor ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) induces an increase of intracellular C(16)-ceramide in sensitive SW480 but not in resistant SW620 cells. | N-palmitoylsphingosine | TNF superfamily member 10 | Homo sapiens |
| 2 | We have previously shown that the death receptor ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) induces an increase of intracellular C(16)-ceramide in sensitive SW480 but not in resistant SW620 cells. | N-palmitoylsphingosine | TNF superfamily member 10 | Homo sapiens |
| 3 | RNAi against CerS6 resulted in a specific and significant decrease of the C(16)-ceramide species, which was sufficient to inhibit TRAIL-induced apoptosis. | N-palmitoylsphingosine | ceramide synthase 6 | Homo sapiens |
| 4 | RNAi against CerS6 resulted in a specific and significant decrease of the C(16)-ceramide species, which was sufficient to inhibit TRAIL-induced apoptosis. | N-palmitoylsphingosine | TNF superfamily member 10 | Homo sapiens |