Title : Sequential RARbeta and alpha signalling in vivo can induce adult forebrain neural progenitor cells to differentiate into neurons through Shh and FGF signalling pathways.

Pub. Date : 2009 Feb 15

PMID : 19100254






1 Functional Relationships(s)
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1 We further show that fibroblast growth factor (FGF) signalling, induces the expression of the retinoic acid degrading enzyme cytochrome P450 (cyp) 26a1, and that one of its products, 4-oxo-RA, mimics the action of the RARalpha agonist in the differentiation of the NPCs into cholinergic neurons. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens