Title : Rheumatoid arthritis in Israeli Jews: shared sequences in the third hypervariable region of DRB1 alleles are associated with susceptibility.

Pub. Date : 1991 Jun

PMID : 1895259






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Two other alleles with the same sequence in the third hypervariable region (amino acids 67-74) but with valine in codon 86 (DR4-Dw14.1/DRB1*0404) or alanine in 85 and valine in 86 (DR1-Dw20, DRB1*0102) gave a combined risk of 3.6 (p = 0.049). Valine major histocompatibility complex, class II, DR beta 4 Homo sapiens