Title : PARP-1 suppresses adiponectin expression through poly(ADP-ribosyl)ation of PPAR gamma in cardiac fibroblasts.

Pub. Date : 2009 Jan 1

PMID : 18815186






1 Functional Relationships(s)
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1 Inhibition of poly(ADP-ribose) polymerase 1 (PARP-1) by 3-aminobenzamide, PJ34, or PARP-1 siRNA markedly increased the transcription of adiponectin and AdipoR1 in cultured fibroblasts, mature 3T3 L1 adipocytes, rat myocardium, and white adipose tissue. 3-aminobenzamide adiponectin receptor 1 Rattus norvegicus