Title : CTCF regulates allelic expression of Igf2 by orchestrating a promoter-polycomb repressive complex 2 intrachromosomal loop.

Pub. Date : 2008 Oct

PMID : 18662993






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Polycomb repressive complex 2 is recruited through the interaction of CTCF with Suz12, leading to allele-specific methylation at lysine 27 of histone H3 (H3-K27) and to suppression of the maternal Igf2 promoters. Lysine SUZ12 polycomb repressive complex 2 subunit Mus musculus