Title : Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage.

Pub. Date : 2008 Aug

PMID : 18602923






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Furthermore, a transgenic mouse model was used to determine the outcome of hepatocyte-specific Smad7 expression on fibrogenesis following CCl(4)-dependent damage. Cefaclor SMAD family member 7 Mus musculus
2 Experimental expression of Smad7 in hepatocytes of mice attenuated TGF-beta signaling and EMT, resulted in less accumulation of interstitial collagens, and improved CCl(4)-provoked liver damage and fibrosis scores compared with controls. Cefaclor SMAD family member 7 Mus musculus