Title : Human polynucleotide phosphorylase reduces oxidative RNA damage and protects HeLa cell against oxidative stress.

Pub. Date : 2008 Jul 25

PMID : 18501193






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Overexpression of hPNPase reduces RNA oxidation and increases cell viability against H2O2 insult. Hydrogen Peroxide polyribonucleotide nucleotidyltransferase 1 Homo sapiens
2 Conversely, hPNPase knockdown decreases viability and increases 8-oxoG level in HeLa cell exposed to H2O2. Hydrogen Peroxide polyribonucleotide nucleotidyltransferase 1 Homo sapiens