Title : Chronic inhibition of the Na+/H+ - exchanger causes regression of hypertrophy, heart failure, and ionic and electrophysiological remodelling.

Pub. Date : 2008 Jul

PMID : 18493245






2 Functional Relationships(s)
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1 BACKGROUND AND PURPOSE: Increased activity of the Na+/H+ -exchanger (NHE-1) in heart failure underlies raised [Na+]i causing disturbances of calcium handling. Calcium sodium/hydrogen exchanger 1 Oryctolagus cuniculus
2 One group of animals were treated with cariporide (inhibitor of NHE-1) in the diet after one month. cariporide sodium/hydrogen exchanger 1 Oryctolagus cuniculus