Title : The expression of Msi-1 and its significance in small intestinal mucosa severely damaged by high-dose 5-FU.

Pub. Date : 2008 Sep

PMID : 18270838






5 Functional Relationships(s)
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1 The expression of Msi-1 and its significance in small intestinal mucosa severely damaged by high-dose 5-FU. Fluorouracil musashi RNA-binding protein 1 Mus musculus
2 OBJECTIVE: The purpose was to investigate the expression of musashi-1 (msi-1) and its significances in small intestinal mucosa that was severely damaged by high-dose 5-FU. Fluorouracil musashi RNA-binding protein 1 Mus musculus
3 OBJECTIVE: The purpose was to investigate the expression of musashi-1 (msi-1) and its significances in small intestinal mucosa that was severely damaged by high-dose 5-FU. Fluorouracil musashi RNA-binding protein 1 Mus musculus
4 RESULTS: After treatment with high-dose 5-FU, the intestinal mucosa suffered severe damage: the villi and crypts disappeared, the number of msi-1-positive cells increased greatly, the intestinal epithelial cells could be divided into two fractions by FACS, and the percentage of msi-1-positive cells was up to 67.75% in the fraction in which the value of FSC was higher. Fluorouracil musashi RNA-binding protein 1 Mus musculus
5 RESULTS: After treatment with high-dose 5-FU, the intestinal mucosa suffered severe damage: the villi and crypts disappeared, the number of msi-1-positive cells increased greatly, the intestinal epithelial cells could be divided into two fractions by FACS, and the percentage of msi-1-positive cells was up to 67.75% in the fraction in which the value of FSC was higher. Fluorouracil musashi RNA-binding protein 1 Mus musculus