Title : Glucosamine and its N-acetyl-phenylalanine derivative prevent TNF-alpha-induced transcriptional activation in human chondrocytes.

Pub. Date : 2007 Nov-Dec

PMID : 18173918






2 Functional Relationships(s)
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1 We analyzed the influence of GlcN and its N-acetyl-phenylalanine derivative (NAPA) on mRNA transcription level of TNF-alpha-stimulated genes in cell culture. Acecainide tumor necrosis factor Homo sapiens
2 RESULTS: Several genes, whose mRNA level was increased by TNF-alpha treatment and significantly reduced by GlcN and NAPA in lbpva55 cells, were identified. Acecainide tumor necrosis factor Homo sapiens