Title : Studies of the mechanism by which increased spermidine/spermine N1-acetyltransferase activity increases susceptibility to skin carcinogenesis.

Pub. Date : 2007 Nov

PMID : 17675337






2 Functional Relationships(s)
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1 In addition, treatment of tumor-bearing K6-SSAT mice with the ODC inhibitor, alpha-difluoromethylornithine, resulted in the complete regression of established tumors. Eflornithine keratin 6 Mus musculus
2 These results indicate that the tumor progression in K6-SSAT mice is dependent on elevated ODC activity and increased putrescine levels and may be further enhanced by oxidative stress. Putrescine keratin 6 Mus musculus