Title : The transmembrane segment S6 determines cation versus anion selectivity of TRPM2 and TRPM8.

Pub. Date : 2007 Sep 21

PMID : 17604279






1 Functional Relationships(s)
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1 In contrast to wild-type TRPM2 channels, currents through the chimera were carried by Cl(-), as demonstrated in ion substitution experiments using the cation N-methyl-D-glucamine (NMDG) and the anion glutamate. Meglumine transient receptor potential cation channel subfamily M member 2 Homo sapiens