Title : Novel processing of Notch 1 within its intracellular domain by a cysteine protease.

Pub. Date : 2007

PMID : 17596709






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Treatment of cells with the gamma-secretase inhibitor L-685,458 resulted in an accumulation of hN1-TMdeltaCT suggesting that this fragment is a gamma-secretase substrate. l-685 Jupiter microtubule associated homolog 1 Homo sapiens
2 Processing towards hN1-TMdeltaCT requires maturation and transport of hN1 to the cell surface since treatment with brefeldin A inhibited its production and resulted in accumulation of hN1. Brefeldin A Jupiter microtubule associated homolog 1 Homo sapiens
3 Processing towards hN1-TMdeltaCT requires maturation and transport of hN1 to the cell surface since treatment with brefeldin A inhibited its production and resulted in accumulation of hN1. Brefeldin A Jupiter microtubule associated homolog 1 Homo sapiens
4 Processing towards hN1-TMdeltaCT requires maturation and transport of hN1 to the cell surface since treatment with brefeldin A inhibited its production and resulted in accumulation of hN1. Brefeldin A Jupiter microtubule associated homolog 1 Homo sapiens