Title : The discovery of new coding alleles of human CYP26A1 that are potentially defective in the metabolism of all-trans retinoic acid and their assessment in a recombinant cDNA expression system.

Pub. Date : 2007 Mar

PMID : 17460545






7 Functional Relationships(s)
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1 The discovery of new coding alleles of human CYP26A1 that are potentially defective in the metabolism of all-trans retinoic acid and their assessment in a recombinant cDNA expression system. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
2 We sequenced CYP26A1 in racially diverse individuals and assessed the metabolism of retinoic acid by newly identified coding alleles of CYP26A1 in a recombinant system. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
3 Wild type CYP26A1 protein metabolized all-trans-retinoic acid (at-RA) to 4-oxo-RA, 4-OH-RA as well as water-soluble metabolites. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
4 Wild type CYP26A1 protein metabolized all-trans-retinoic acid (at-RA) to 4-oxo-RA, 4-OH-RA as well as water-soluble metabolites. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
5 Wild type CYP26A1 protein metabolized all-trans-retinoic acid (at-RA) to 4-oxo-RA, 4-OH-RA as well as water-soluble metabolites. 4-oxoretinoic acid cytochrome P450 family 26 subfamily A member 1 Homo sapiens
6 Wild type CYP26A1 protein metabolized all-trans-retinoic acid (at-RA) to 4-oxo-RA, 4-OH-RA as well as water-soluble metabolites. 4-oh-ra cytochrome P450 family 26 subfamily A member 1 Homo sapiens
7 Wild type CYP26A1 protein metabolized all-trans-retinoic acid (at-RA) to 4-oxo-RA, 4-OH-RA as well as water-soluble metabolites. Water cytochrome P450 family 26 subfamily A member 1 Homo sapiens