Title : Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and Cyp2e1(-/-) mice.

Pub. Date : 2007 Jul

PMID : 17392391






1 Functional Relationships(s)
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1 However, we previously found that alcohol [ethanol and isopentanol (EIP)] causes increases in APAP hepatotoxicity in Cyp2e1(-/-) mice, indicating that CYP2E1 is not essential. isopentyl alcohol cytochrome P450, family 2, subfamily e, polypeptide 1 Mus musculus