Title : Identification of a novel human glucagon receptor promoter: regulation by cAMP and PGC-1alpha.

Pub. Date : 2007 May 15

PMID : 17374560






1 Functional Relationships(s)
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1 Expression of peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha), known to be upregulated in the liver by fasting, was found to abolish the cAMP-dependent downregulation of glucagon receptor mRNA expression in vitro, whereas overexpression of PGC-1beta had no effect. Cyclic AMP PPARG coactivator 1 beta Homo sapiens