Title : The cyclin-dependent kinase Cdc28p regulates multiple aspects of Kar9p function in yeast.

Pub. Date : 2007 Apr

PMID : 17251549






5 Functional Relationships(s)
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1 In the first mechanism, phosphorylation at serine 496 recruits Kar9p to one SPB. Serine Kar9p Saccharomyces cerevisiae S288C
2 A phosphomimetic mutation at serine 496 bypasses the requirement of BIK1 and CLB5 in generating Kar9p asymmetry. Serine Kar9p Saccharomyces cerevisiae S288C
3 In the second mechanism, Clb4p may target serine 197 of Kar9p for phosphorylation. Serine Kar9p Saccharomyces cerevisiae S288C
4 This modification is required for Kar9p to direct cMTs to the bud. cmts Kar9p Saccharomyces cerevisiae S288C
5 We propose that phosphorylation at serine 197 regulates the release of Kar9p from Stu2p at the SPB, either to clear it from the mother-SPB or to allow it to travel to the plus end. Serine Kar9p Saccharomyces cerevisiae S288C